Given a protein sequence alignment, and a classification of some or all of the sequences in the same alignment into functional or other sub-types, PROUST-II predicts positions in the alignment and particular amino acids in them that confer the specific types. For more information, click here.
The server was updated and checked August 2002. I expect there still may be some teething problems related to different platforms and so forth, so if it doesn't work, then let me know (robert.russell@bioquant.uni-heidelberg.de).
If you have an alignment, and a groups file, click on SUBMIT (left) to run the program.
If want to find out how to run the program, or for and explanation of what the program does, click HELP.
For a complete description of the method S.S. Hannenhalli & R.B. Russell, Analysis and prediction of protein sub-types from multiple sequence alignments J. Mol. Biol. 303, 61-76, 2000. PubMed